Fruit fly muscles with a hypertrophic cardiomyopathy mutation don’t relax properly

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10/12/2017 02:03 PM EDT

fruit fly flight muscles intact

Using fruit flies, Johns Hopkins researchers have figured out why a particular inherited human heart condition that is almost always due to genetic mutations causes the heart to enlarge, thicken and fail. They found that one such mutation interferes with heart muscle’s ability to relax after contracting, and prevents the heart from fully filling with blood and pumping it out.

Full story at http://www.hopkinsmedicine.org/news/media/releases/fruit_fly_muscles_with_a_hypertrophic_cardiomyopathy_mutation_dont_relax_properly

Source
Johns Hopkins Medicine

This is an NSF News From the Field item.